Technically superior for critically ill
Combination has activity against a variety of gram+ve and gram -ve aerobic and anaerobic bacteria.
Susceptible bacteria Include :
● Aerobic and facultative gram -ve microorganisms: Staphylococcus aureus
● Aerobic and facultative gram-ve microorganisms: Acinetobacter baumannii, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, and Pseudomonas aeruginosa
● Gram-ve anaerobes: Bacteroides fragilis group (B.fragilis, B.ovatus, B.thetaiotaomicron, and B.vulgatus)